Cellular networks controlling Th2 polarization in allergy and immunity
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Cellular networks controlling Th2 polarization in allergy and immunity
In contrast to the development of Th1 (type 1 T helper cells), Th17 and Treg (regulatory T cells), little is known of the mechanisms governing Th2 development, which is important for immunity to helminths and for us to understand the pathogenesis of allergy. A picture is emerging in which mucosal epithelial cells instruct dendritic cells to promote Th2 responses in the absence of IL-12 (interle...
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ژورنال
عنوان ژورنال: F1000 Biology Reports
سال: 2012
ISSN: 1757-594X
DOI: 10.3410/b4-6